@article {Conway:December 2007:0960-1643:953,
	author = "Conway, Shaun",
	author = "Hart, Andrew",
	author = "Clark, Allan",
	author = "Harvey, Ian",
	title = "Does eating yogurt prevent antibiotic-associated diarrhoea? A placebo-controlled randomised controlled trial in general practice",
	journal = "British Journal of General Practice",
	volume = "57",
	year = "December 2007",
	abstract = "<B>Background:</B> Probiotic capsules have been shown to reduce the incidence of antibiotic-associated diarrhoea in a number of settings. If probiotic yogurt were equally efficacious then it would provide a simple and cost-effective means of preventing antibiotic-associated diarrhoea.<P></P><B>Aim:</B> To investigate whether eating live bio yogurt at the time of taking oral antibiotics can prevent antibiotic-associated diarrhoea.<P></P><B>Design of study:</B> This study was a three-arm (bio yogurt, commercial yogurt, no yogurt) randomised controlled trial with double blinding between the two yogurt arms.<P></P><B>Setting:</B> A single primary care general practice surgery in Hingham, Norfolk. The study population included all ages except babies.<P></P><B>Method:</B> Patients aged over 1 year who required a 1-week course of antibiotics were included in the study. There was complete follow up for 369 patients. The intervention was the consumption of 150 ml of live strawberry-flavoured yogurt for 12 days, starting on the first day of taking the antibiotic. Diarrhoea was defined as 'three or more loose stools per day over at least 2 consecutive days' within 12 days of starting the antibiotics.<P></P><B>Results:</B> Of the 120 patients in the no-yogurt group, 17 (14%, 95% confidence interval [CI] = 9.0 to 21.5) developed diarrhoea. Of the 118 given commercial yogurt, 13 (11%, 95% CI = 6.6 to 17.9) developed diarrhoea; nine of the 131 patients (7%; 95% CI = 3.7 to 12.5) given bio yogurt developed diarrhoea (<I>P</I> = 0.17).<P></P><B>Conclusion:</B> Overall, this study failed to demonstrate that yogurt has any effect on antibiotic-associated diarrhoea.",
	pages = "953-959(7)",
	url = "http://www.ingentaconnect.com/content/rcgp/bjgp/2007/00000057/00000545/art00006"
	doi = "doi:10.3399/096016407782604811"
}